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KMID : 0363319760010010092
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Journal of Korean Oriental Internal Medicine
1976 Volume.1 No. 1 p.92 ~ p.97
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EFFECT OF DIETARY PANAX GINSENGS ON THE RATE OF THE BLOOD ETHANOL CLEARANCE
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Abstract
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Upon feeding dried Ginseng to rats of either low-protein or high protein diet ethanol was administered intraperitoneally and disappearance rate blood alcohol was enzymatically measure. In terms of residual blood alcohol after a time lapse of 3.5 hours between intraperitonial administration and blood withdrawal neither´ ginseng nor ginseng plus 40% casein did improve the rate, of alcohol clearance but sexual differeiioe was clearly demonstrated in favor of female rats. In the case of blood withdrawn only 2 hours after intraperitoneal injection of alcohol, the tendency of female superiority in alcohol clearance rate is demonstrated when a comparison is made among the groups fed with ginseng and this was particularly true is groups of rats fed with basal diet plus l percent ginseng residual blood ethanol being 15.4 mg/ml vs. 8.8mg/ml.
Liver homogenate alcohol dehydrogenase activity measured in terms of residual ethanol content after in vitro reaction on which a known amount of alcohol was added clearly demonstrated a male superiority in alcohol clearance.
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KEYWORD
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